Effectiveness of Platelet-Rich Fibrin (PRF) Following Mandibular Third Molar Extraction: A Systematic Review

(1) Purpose: The employment of platelet-rich fibrin (PRF) in the extracted teeth socket has been shown to aid tissue healing. It also minimizes detrimental consequences. rationale this systematic review is observe possible association between PRF and postoperative consequences following mandibular third molar surgery. (2) Materials Methods: databases were explored electronically (till 28 February 2021): PubMed, Cochrane library, Embase, International Clinical Trials Registry Platform (ICTRP), ClinicalTrials.gov. A manual explore was accomplished on various journals regarding subject oral maxillofacial online applied keywords “platelet-rich or PRF,” “mandibular molar.” To efficiency PRF, accompanying post-operative collected: pain, swelling, trismus, inter-incisal distance, analgesic consumption, soft healing, bone complications, periodontal parameters. (3) Results: Just 9 full-text studies out 26 comprised for qualitative analysis. All randomized clinical trials (RCTs), with eight split-mouth designs one parallel design study. Significant outcomes usually observed mouth opening, pocket depth, incidence alveolar osteitis dry sockets, but not constantly. scrutiny disclosed that had no considerable outcome (4) Conclusions: Local administration a practical way alleviating oedema, enhancing healing extraction. tends have function More controlled RCTs are necessitating exploring end results